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In particular, founder effects and recent strong population size reductions, such as those experienced by the indigenous peoples of the Americas, have severe impacts on genetic variation that can lead to the accumulation of large allele frequency differences between populations due to genetic drift rather than natural selection

[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Wright ME, Groshong SD, Husgafvel-Pursiainen K, Genova E, Lucia MS, et al

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